These plants will have a lot more details displayed including an image. Spreads beautifully over the ground and seems easy to please as to soil (I have it in a fast-draining, coarse soil w/ a pH of 7.5); cascades over the side of raised beds (ironwort, mountain tea), an endemic plant of the Balkan Peninsula, has been used in traditional medicine in the treatment of gastrointestinal complaints, inflammation, and rheumatic disorders. The scent of this is one of my favorites on earth, and it makes a wonderful mild tea. Age-synchronization of the worms was performed according to the method of Guerrero-Rubio et al.26. Something wrong with this post? A comely plant, highly desired for those of us blessed with hot, dry summers and cool, moist winters. *P < 0.05, **P < 0.01, compared with control. It is used as herbal tea and/or in the phytotherapy since the ancient times (ANEVA et al., 2018; TODOROVA & TRENDAFILOVA, 2014). As an herbal tea (herbal infusion technically) it is known for its antioxidants, which come in the form of polyphenols and flavonoids. Sharing links are not available for this article. Description This tough, drought and heat-tolerant plant is native to the mountains surrounding the Mediterranean sea, especially the Peloponnese. 29 as of April 7, 2000 (100) Various medicinal properties have been ascribed to natural herbs. This is the first report to evaluate and analyze the antiaging effect of S. scardica. Besides its useful characteristics as medicinal plant, S. scardica is a species of high conservation value. The experiment was performed with 5 plates, each plate holding 10 worms. The results were obtained from 3 independent experiments with 10 worms in each experimental group. Power plant Sideritis scardica. SOM 1391. Additionally, under heat stress, the pretreatment of SHWE improved the survival rate of GR1307 worms, a knockout mutant of daf-16. After that, randomly selected worms were transferred to sample-free NGM agar plates and exposed to heat stress for 2 hours at 35°C. The plant is native to the Balkan and occurs in south-west Albania, Macedonia, Bulgaria, Serbia, Greece and Turkey. ; Sideritis clandestina (Bory & Chaub. The record derives from WCSP (data supplied on 2012-03-23 ) which reports it as an accepted name (record 191627 ) with original … Traditional usage (TWM): colds and restless insomnia. Please check you selected the correct society from the list and entered the user name and password you use to log in to your society website. Compared with the control value, the average life span of the wild strain of C. elegans was increased by approximately 15% at a SHWE concentration of 5 µg/mL and by approximately 22% at a SHWE concentration of 50 µg/mL. Plant material was collected and identified by … In order to confirm the improvement of heat stress tolerance by SHWE treatment, the survival rate under heat stress was measured using N2 worms. Create a link to share a read only version of this article with your colleagues and friends. As a result of culturing at 35°C, N2 worms precultured on NGM agar plates containing SHWE at 500 µg/mL maintained a significantly higher survival rate than the control group (Figure 3). Sunagawa, T., Shimizu, T., Kanda, T., Tagashira, M., Sami, M., Shirasawa, T. Prasanth, M., Sivamaruthi, B., Chaiyasut, C., Tencomnao, T. Guerrero-Rubio, MA., Hernández-García, S., García-Carmona, F., Gandía-Herrero, F. View or download all content the institution has subscribed to. HSP-16.2 is a small HSP in C. elegans, and its expression is induced by heat and oxidative stress.15 It has been pointed out that increasing the expression level of HSP-16.2 in cells has a prolonged life span effect on C. elegans.16 The TJ375 strain of C. elegans is a genetically modified worm with a hsp-16.2 promoter linked to a green fluorescent protein (GFP) reporter, enabling visualization of HSP-16.2 expression in response to the stress. The data are expressed as mean ± standard error. Lin, K., Dorman, JB., Rodan, A., Kenyon, C. Crombie, TA., Tang, L., Choe, KP., Julian, D. Wilson, MA., Shukitt-Hale, B., Kalt, W., Ingram, DK., Joseph, JA., Wolkow, CA. The worms were cultured at 25°C, and their viability was determined every 2 days. Rated 5.00 out of 5 based on 2 customer ratings (4 customer reviews) $ 7.50. The mammalian genome encodes 4 FOXO proteins, while genomes of Caenorhabditis elegans and Drosophila melanogaster encode only 1 FOXO homolog, DAF-16 and dFOXO, respectively.7 FOXO is responsible for activating genes involved in various cellular stress responses including autophagy, apoptosis, and stress resistance.8 Therefore, it has been pointed out that increasing cellular expression of these proteins may contribute to prolonging the life span of living organisms. Strictly Medicinal LLC PO Box 299 Williams, OR 97544 USAFax: (541) 846-0872Email:[email protected]Copyright © 2021. You can be signed in via any or all of the methods shown below at the same time. You, or anyone with the link, can use it to retrieve your Cart at any time. is an accepted name This name is the accepted name of a species in the genus Sideritis (family Lamiaceae ). Sideritis is a good herbal remedy for countering Respiratory troubles namely Flu and Cold. Figure 1 shows the survival curves of N2 worms cultured on modified nematode growth medium (mNGM) agar plates containing SHWE under normal culture conditions. As a first step, a hot water extract of S. scardica (SHWE) was prepared and tested for its effect on the life span of a wild strain (N2) of C. elegans. Simply select your manager software from the list below and click on download. Sideritis scardica. Toshiyuki Shibata https://orcid.org/0000-0001-5639-8511. As a second step, we analyzed the expression of HSP and DAF-16/FOXO using transgenic mutants of C. elegans and then investigated the bioactivities of S. scardica. Rate of N2 worms treated with 50 worms of type GR1307 25°C, and the obtained powder... Tea starter seedling extraction technique mostly fine the modified nematode growth medium agar and. C18 column greenhouse, zone 5, have been on the survival rate of GR1307 worms, few! ( if sown directly into pots etc Journals Sharing page are abundant in Mediterranean,. 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