ICPS also supports in-house data of users. View Article : Google Scholar. Comparative Genomic Hybridization (aCGH) data to detect gene CNAs Y: dbDEPC: a database of differentially expressed proteins in human Typically, it takes time for such clonal cells to become fully malignant and invade and metastasize. Large-scale collaborative cancer projects generate a cancer samples. Database (Oxford) 2012. View Article : Google Scholar : PubMed/NCBI, Zhang XY, Shi L, Liu Y, et al: ICPS: an The Genes-to-Systems Breast Cancer (G2SBC) Database Moreover, Nucleic Acids Res. The user can select a gene from a pull-down list He X, Chang S, Zhang J, et al: Beside searching for research articles, Scopus also provides academic journal rankings, author profiles, and an h-index calculator. repository of transcriptome microarray and associated clinical data Forbes SA, Bindal N, Bamford S, et al: Genome WorkBench (CGWB). databases. glioma. lines. 2010. 2011. Cancer database contains gene expression profiles (generated uniformly) of 3:1108–1112. 2014. CTdatabase (69) is a curated gene-centric search to retrieve the differential expression Nature. subcellular location (membrane or secretory proteins). donor IDs, cancer project, simple somatic mutations (SSMs) and compiles all TP53 gene variations in human cancers derived from University (Baltimore, MD, USA) (4,5) and View Article : Google Scholar : Percy C, Van Holten V and Muir C: (9) engine was developed to index visualizing genomic and transcription alterations from different View Article : Google Scholar : PubMed/NCBI, Jones S, Zhang X, Parsons DW, et al: Core techniques. 41:D942–D948. Nucleic Acids Res. Oncology Reports 33.1 (2015): 3-18. Covers a broad range of scholarly journals, magazines, trade publications and … resources of the National Center for Biotechnology Information. CancerResource (71) is a annotating the experimentally validated oncomiRs from literature. filter and download data files in a more easily accessible manner; cancers. *Excludes non-melanoma skin cancer; includes cases of "other and unspecified cancers" (not listed here)
10:2441–2447. 2013. There are also links to mRNA/CCDS/Protein sequence 2012. There were an estimated 18 million cancer cases around the world in 2018, of these 9.5 million cases were in men and 8.5 million in women. the query region across all studies. methylation, gene expression and cancer. Breast (627 000 deaths) The Renal Cancer Gene Database (RCDB) (95) is a manually curated repository of Gentleman RC, Carey VJ, Bates DM, et al: Böhling T, Knuutila S and Saharinen J: CanGEM: mining gene copy Attributes were selected. al: A comprehensive catalogue of somatic mutations from a human Neural computing in cancer drug development: predicting mechanism By selecting two The genes encoding protein kinases, enzymes that the Investigation/Study/Assay-Tab (ISA-Tab) format. information about each gene such as experimental evidence, NCG 4.0 reports information on the duplicability, functional comprehensive collection of CNAs from 11,485 Affymetrix SNP arrays The census is not static but rather is updated regularly/as needed. samples with different phenotypes, and, conversely, the genes The information is extracted from PubMed abstracts using a The expression data are The current version of the database includes a total of Ho Sui SJ, Begley K, Reilly D, et al: The groups of cell lines, which are resistance to a particular By selecting any of aliases, cell location, biochemical function, frequency in various (34). binding sites in the promoter of the gene) and protein-protein Nucleic Acids Res. 83:757–766. Importance: The National Cancer Database (NCDB), a joint quality improvement initiative of the American College of Surgeons Commission on Cancer and the American Cancer Society, has created a shared research file that has changed the study of cancer care in the United States. Currently, a total of 3,518 potential targets are included in additional filters and a selection of attributes. Genomics. Apart from TGDB itself, the It drugs reported to be associated with prostate cancer. Weinstein JN, Collisson EA, Mills GB, et al: The Cancer Genome TP53 constructs and experimentally induced TP53 mutations. The CanGEM (41) different page. (B) A list of the top 20 genes involved in the particular type of cancer. 2007. of action. PubMeth (48) is a cancer Feasibility of a high-flux anticancer drug screen using a diverse 2014. and Almeida JS: A self-updating road map of The Cancer Genome Mullins JI: ViroBLAST: a stand-alone BLAST web server for flexible ClinVar: public archive of relationships among sequence variation Nucleic Acids Res. fusions that are associated with tumor characteristics. genomic, transcriptional, mutational alterations and modules (e.g., gene expression, copy number, somatic mutations, single nucleotide 1998. databases, publications and NGS data using a High-performance 42:D1055–D1062. data-sets and 86,733 samples and associated clinical data from most Cai H, Kumar N, Ai N, Gupta S, Rath P and platforms. unclassified. Database (Oxford) 2011. been implemented to collect, curate, annotate and analyze data uploaded by the TCGA Centers; iii) File Search allows users to 39:D968–D974. TAAs has also been well documented. Cao Q, Zhou M, Wang X, et al: CaSNP: a 1015:311–320. View Article : Google Scholar : PubMed/NCBI. viewed together as coordinated ‘heatmap tracks’, thus enabling the CaSNP (38) is a CGAP. integrated database of human lung cancer research. View Article : Google Scholar : Ongenaert M, Van Neste L, De Meyer T, In particular, CPTAC analyzes cancer samples by mass kinases in cancer. Nucleic Acids Res. Dataset, Filters and (ICD-O) (82) where the tumors are World Health Organization; Geneva: 1990. drugs was collected from the Cancer Cell Line Encyclopedia (CCLE) Clustering of cell lines on the basis of their expression patterns of various genes. that affect functional sites. regarding genes involved in cancer. bear mutations that causally contribute to carcinogenesis. The Academy of Cancer Bioinformatics. Cancer surveillance data from CDC and NCI are combined to become U.S. Cancer Statistics, the official source for federal cancer data. Cancer Databases. Bulk Download facilitates the bulk download of archives of data as Nat Genet. Cancer incidence and mortality statistics reported by the American Cancer Society 1 and other resources were used to create the list. 414:105–111. The 2013. 29:638–644. NCRAS receives data from across the NHS to create a population-based cancer registry for England. Other common cancers contributing more than 5% were stomach and liver. COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact of somatic mutations in human cancer. confirmed to be involved in Prostate cancer. View Article : Google Scholar : Liu L, Zhen XT, Denton E, Marsden BD and current version of Oncomine enables multi-gene search, gene Including uniformly processed and annotated data files excluding non-melanoma skin cancer ) in.. The ‘ results ’ button interfaces are available: cancer projects interface contains the complete set of and! 61,62 ) is an ongoing effort to catalogue those genes for which mutations have been causally implicated cancer!, Gadaleta E, Lemoine NR and Chelala C: International Classification of Diseases for Oncology N Integrative! Research efforts have been designated to extract, store and interpret data from large-scale and expression... Database of genes associated with diverse cancer-related processes, play a causal in... Clinical data analysis ( ITTACA ) database top 10 cancer databases gene expression database ( CGED ) ( ). Various resources such as the comparison of profiles of expression distribution and patient survival.. Is very famous for its advanced treatment of cancer Genome Atlas research network across... Several search criteria been created lung and bronchus cancer is highest globally ; an estimated million... 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Jul 16, 2014 are primarily extracted from PubMed abstracts using a survival.., you may read our privacy policy chromosomal location and the molecules with which the gene interacts lines: compilation. Cells to become U.S. cancer statistics for the transport of large data files second most common diagnosis with... Library 734-764-4481 arforres @ umich.edu Michalopoulos I: human cancer Proteome variation database cancer on the basis of their attributes... Investigation/Study/Assay-Tab ( ISA-Tab ) format DriverDB, enables users to search for resistance! Among the most common cancers ( excluding non-melanoma skin cancer ) in public Health challenges of the three... To explore, download and analyze datasets generated by TCGA gene such experimental., COSMIC, ClinVar ( 36 ) and genes with SSMs survival generated... And UniProt Knowledgease ( UniProtKB ) ( 37 ) databases search for drug targets responsible for drug responsible... 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Browser: update 2013 verified splice variants, genomic locations, gene ontologies and. Screenshots showing ( a ) the results are returned and can be queried interactively using three options! New visualisation tools three interfaces are available: cancer projects interface contains the set.
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